CRISPR Cas9 has been described as the greatest biological breakthrough in decades. The hopes resting on this gene editing technology are immense - this week a Swiss drug company announced it is beginning a landmark clinical trial using CRISPR on a patient with a dangerous blood disease. Mark Coles profiles one of the creators of the technology, the American biochemist Jennifer Doudna. Clarification: In 2018 a federal court confirmed that the patents granted by the United States Patent and Trademark Office to the Broad Institute, MIT and Harvard concerning CRISPR editing of eukaryotic genomes do not interfere with patent claims filed by the University of California, Berkeley where Jennifer Doudna is based. A new decision in February 2019 has granted Jennifer Doudna and her team the patent at the heart of this intellectual property dispute. Jennifer Doudna and her team have been granted several substantial patents for CRISPR technology.Presenter: Mark Coles
Producers: Viv Jones, Tural Ahmedzade
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Folge vom 02.03.2019Jennifer Doudna
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Folge vom 23.02.2019Luciana BergerMP Luciana Berger resigned from the Labour Party this week to join the newly-formed Independent Group. For years she has been the target of sustained anti-Semitic abuse, and has criticised the Labour Party's handling of the issue. One of the reasons she gave for leaving the party is that she has come to view it as "institutionally anti-Semitic”. Her resignation comes within days of her facing a vote of no-confidence in her Liverpool Wavertree constituency, which was withdrawn after a bitter row.Presenter: Becky Milligan Producer: Viv Jones, Tural Ahmedzade Editor: Penny Murphy
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Folge vom 16.02.2019Chris GraylingThe transport secretary's critics call him “failing Grayling" - an unkind nickname, perhaps, but one made more likely to stick by his infamous decision to award a valuable contract to a Brexit ferry company with no ferries. He cancelled the contract this week amid much derision in Parliament. Presenter: Mark Coles Producer; Sally Abrahams
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Folge vom 09.02.2019David AdjayeWe’re talking buildings and monuments on Profile this week – looking at the life and career of Sir David Adjaye. The 52-year-old British-Ghanaian architect shot to fame in the US for his 2016 Museum of African American History and Culture in Washington DC. An exhibition featuring his work has just opened in London. Producer: Sally Abrahams Presenter: Mark Coles