Science In Action Folgen

DNA has revealed potential animal COVID carriers at the Wuhan market, but what does that tell us about the start of the pandemic? Roland talks to two of the experts behind the new analysis: Dr Florence Débarre and Professor Eddie Holmes.Also, we look into Europe’s grand new space ambitions. ESA director general Josef Aschbacher gives Roland the details of the space agency’s out-of-this-world plans.And Beethoven's last DNA: a hairy story of his family and genetic afflictions. Dr Tristan Begg shares how the composer’s tresses unlocked new information about his life and death.Image credit: Eddie HolmesProducer: Roland Pease Assistant producer: Sophie Ormiston

34 days after it first formed at the far end of the Indian Ocean, record-breaking Cyclone Freddy made a repeat landfall on Mozambique as well as passing over Malawi, causing extensive damage and loss of life. Climate scientists Liz Stephens and Izidine Pinto join Roland to give an update on the destruction and explain how Cyclone Freddy kept going for an exceptionally long time.At the Third International Human Genome Summit in London last week, Professor Katsuhiko Hayashi announced he had created baby mice from eggs formed by male mouse cells. Dr Nitzan Gonen explains the underlying science, whilst Professor Hank Greely discusses the ethics and future prospects.And from one rodent story to another, SARS-CoV-2 has been detected in brown rats scurrying around New York sewers. Dr Thomas DeLiberto from the US Department of Agriculture gives Roland the details.Image credit: Jack McBrams/Getty ImagesProducer: Roland Pease Assistant Producer: Sophie Ormiston

Human Genome Editing: The team meet experts at the Human Genome Editing Summit in London, seeking to cure genetic disease and ensure that it's safe and available to all. Roland Pease hears from Victoria Gray, the first person to be cured of the debilitating and life-shortening disease sickle cell anaemia by gene editing, and from the scientists making it possible. Also, the prospect of work to attempt gene rescue in fetuses before they are born. But the technology is expensive and complex – the question troubling the participants is to ensure people across the world can benefit from it, not just the rich and privileged. And what are the limitations of gene editing? Can it be made more effective, safer? And what of gene edits that will be inherited by future generations?