The warning that floods are likely to become more common, or more severe, won't be a high priority for those with homes currently deluged. But it is something architects, engineers and planners have been taking very seriously. Dr. Adam Rutherford finds out about some of the innovations, both in UK and abroad, being designed for homes in areas prone to flooding - from simple door guards and waterproofing which can be retrofitted to existing houses - to entire city re-landscaping, or 'waterscaping' which aims to make room for the river, rather than fighting against it.Last week Adam talked about research showing that most people of European or East Asian descent carry a small percentage of Neanderthal DNA - about 2%. He examined some of the physical characteristics we may have got from the genes of our ancient cousins. This week Inside Science addresses some of the questions this fascinating work prompted.A new study in the journal Neuron this week, looks at what happens in the brain when one of the senses is dulled. Dr. Patrick Kanold, from the University of Maryland in the States, and his colleagues simulated blindness in mice by keeping them in the dark for a week, to see what happened to the parts of their brains involved in hearing. The found that the mouse's hearing improved. We sometimes talk about the brain being 'hardwired': all the neurons locked in place from early childhood. It was assumed that there was only a short, finite period when the brain was still capable of changing, but the new research shows parts of the brain still has room to manoeuvre.A recurring problem in science is that we are far better at collecting vast amounts of scientific data than we are at actually analysing them. To combat this problem, the charity Cancer Research UK have just launched a mobile phone game, 'Genes In Space', that farms statistical analysis out to the masses. Under the guise of flying a spaceship through a meteor storm, game players actually navigate their way through genetic sequence data from breast cancer patients. The information on the virtual path they take is automatically uploaded to the database and fed back into the scientific process.Producer: Fiona Roberts.
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Folge vom 06.02.2014Engineering for floods; Neanderthal genes; Switching senses; Genes in Space game
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Folge vom 30.01.2014Neanderthals; Plague; Wind Tunnel; Music Timing; Stem CellsWe now know that Neanderthals and our ancestors interbred over 40,000 years ago. Recent research has shown that most people of European or East Asian descent carry a small percentage of Neanderthal DNA - about 2%. But two new papers this week examine some of the physical characteristics we may have got from the genes of our ancient cousins. They include some disease susceptibilities and hair and skin characteristics, which may have helped our forebears survive in northern climes.There have been many sensationalist headlines in the news this week suggesting that the deadly bubonic plague could return, when really, it never went away. And while it can still be deadly, it can be treated early with antibiotics. In the Middle Ages the Black Death is thought to have killed up to half of the European population and so too did the Justinian Plague 800 years earlier. Now scientists have compared these two plague genomes to find that they were both caused by distinct strains of the same bacterium, Yersinia Pestis. Knowing how the pathogen evolved in the past is crucial to our understanding of possible future strains of plague. Lead author Dr David Wagner from the University of Arizona tells Dr Adam Rutherford that it's very unlikely the plague will return on a mass scale.It's a windy Show Us Your Instrument this week - Prof Konstantinos ('Kostas') Kontis, Professor of Aerospace Engineering shows us around his wind tunnel. It's used to help develop more effective plane wings, helicopter rotors, and wind turbine blades, but cyclist Sir Chris Hoy has also been a test sample. Glasgow University is currently building a hypersonic wind tunnel, which can test air flow at speeds of up to Mach 10.We all unconsciously synchronise our movements and researchers at the University of Birmingham have shown how professional musicians make tiny adjustments in their playing to keep time with their colleagues. Alan Wing, Professor of Human Movement in Psychology tells Adam how this research about minute synchronisation is helping to inform how robots can be designed to interact with humans.Stem cells can become any other cell in the body from nerve to bone to skin, and they are touted as the future of medicine. Embryos are one, often ethically charged, source of stem cells and in 2006 Nobel prize winning research showed that skin cells could be "genetically reprogrammed" to become stem cells. These were called induced pluripotent stem cells. Scientists in Japan have now shown, in mice, that this previous painstaking method of making the versatile cells can be replaced by little more than a short dip in acid. Professor Chris Mason from University College London tells Adam that this major breakthrough could be faster, cheaper and possibly safer than other cell reprogramming technologies.Producer: Fiona Hill.
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Folge vom 23.01.2014Higgs Boson; Neutrinos; Antarctic echo locator; Rainforest fungi; Alabama rotThe Higgs boson has been discovered, providing the final piece of the jigsaw puzzle for the Standard Model of particle physics, a description of how the universe works. But what physicists haven't found yet, which they should have, are supersymmetry or SUSY particles. Roland Pease attended a recent meeting of top physicists, and shares with Adam Rutherford the latest discussions about where to look next.The history of neutrinos is littered with interesting characters. It was Wolfgang Pauli who first suggested their existence. Pauli was so unsettled by his proposal that he bet a case of champagne against anyone being able to discover these "pathologically shy" particles. Since then, scientists have built ever more elaborate experiments to try and detect these particles. Ray Jayawardhana, Professor of Astrophysics and author of a new book "The Neutrino Hunters" explains more about the most abundant particle in the universe.This week's Show Us Your Instrument is a tool used to help scientists measure the glaciers in the Antarctic. Julian Dowdeswell, a glaciologist from the University of Cambridge, uses an echo-locator to look at the dynamics of large ice masses and their response to climate change.Fungi, not viewed favourably by gardeners, can be good for rainforest biodiversity. Dr Owen Lewis from Oxford University tells Melissa Hogenboom that plots sprayed with fungicide soon become dominated by a few species at the expense of many others, leading to a marked drop in diversity.A mysterious illness killing dogs has been in the headlines this week. David Walker a veterinary specialist, says that although it's not clear what's causing the disease, people should not panic.
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Folge vom 16.01.2014Personal genetics kits; Persister cells; Earthquake mapping; ScorpionsFor a couple of hundred quid, one of many companies will send you a kit for sampling your own genome, and most will tell you your genetic risk for some diseases. In December the US Food and Drug Administration imposed a ban on one of these companies, 23andme. The reasoning was that if the organisation is offering medical advice, it needs to be medically regulated. Geneticist Professor Robert Green from Harvard Medical School argues that people can cope responsibly with their genetic information and that the FDA is being over-cautious.Most people are familiar with recurrent infections caused by bacteria such as tonsillitis and bladder infections, where you pick up an infection, get treated with antibiotics and then after a few weeks or months the infection reappears and you need another course of antibiotics; this is a problem that can go on for many years, and is a major healthcare burden world-wide. Marnie Chesterton met a team from Imperial College studying the elusive persister cells responsible for these relapses.Earthquakes usually occur in subduction zones, where one tectonic plate plunges beneath another. Now a team at University of Aberdeen has analysed a large earthquake database and developed a global map giving clues to which areas could be capable of causing giant earthquakes. Professor Nicholas Rawlinson explains the difficulties of predicting.The venom of scorpions contains neurotoxins, which attack the nervous system of animals - it's one of the reasons why it's not a good idea to be stung by a scorpion. The structure of these toxins very closely resembles the structure of a group of proteins with a completely different purpose, called defensins. Professor Jan Tytgat from KU Leauven suggests that venom evolved from these defensins.