Science Friday Folgen

When it comes to the eventual end of our universe, cosmologists have a few classic theories: the Big Crunch, where the universe reverses its expansion and contracts again, setting the stars themselves on fire in the process. Or the Big Rip, where the universe expands forever—but in a fundamentally unstable way that tears matter itself apart. Or it might be heat death, in which matter and energy become equally distributed in a cold, eventless soup. These theories have continued to evolve as we gain new understandings from particle accelerators and astronomical observations. As our understanding of fundamental physics advances, new ideas about the ending are joining the list. Take vacuum decay, a theory that’s been around since the 1970s, but which gained new support when CERN confirmed detection of the Higgs Boson particle. The nice thing about vacuum decay, writes cosmologist Katie Mack in her new book, The End of Everything: (Astrophysically Speaking), is that it could happen at any time, and would be almost instantaneous—painless, efficient. Mack joins Ira to talk about the diversity of universe-ending theories, and how cosmologists like her think about the big questions, like where the universe started, how it might end, and what happens after it does.  Over the years, researchers have created thousands of chemical dyes that fluoresce in every color of the rainbow—but there’s a catch. Most of those dyes fluoresce most brightly when they’re in a dilute liquid solution. Now, researchers say they’ve created what they call a “plug-and-play” approach to locking those dyes into a solid form, without dimming their light.   The new strategy uses a colorless, donut-shaped molecule called a cyanostar. When combined with fluorescent dye, cyanostar molecules insulate the dye molecules from each other, and allow them to pack closely together in an orderly checkerboard—resulting in brightly-fluorescing solid materials.  Amar Flood, a professor of chemistry at Indiana University, says the new materials can be around thirty times brighter than other materials on a per-volume basis, and the approach works for any number of off-the-shelf dyes—no tweaking required. Flood joins SciFri’s Charles Bergquist to discuss the work and possible applications for the new technology. Scientists at Woods Hole Marine Biological Laboratory recently thrilled the genetics world by announcing they’ve successfully knocked out a gene in squid for the first time.  “I’m like a kid in a candy store with how much opportunity there is now,” says Karen Crawford, one of the researchers and a biology professor at St. Mary’s College of Maryland. Crawford explains this modification has huge implications for the study of genetics: Squids’ big brains mean this work could hold the key to breakthroughs in research for human genetic diseases, like Huntington’s disease and cystic fibrosis. Joining Ira to talk about the news are Crawford and her co-lead on the research, Josh Rosenthal, a senior scientist at the Marine Biological Laboratory in Woods Hole, Massachusetts.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

As the COVID-19 pandemic has spread, it’s become clear certain populations are particularly at risk—including those serving sentences in prisons and jails. The virus has torn through correctional and detention centers across the U.S., with more than 78,000 incarcerated people testing positive for COVID-19 as of July 28, according to the Marshall Project’s data report.  “Prisons are just the worst possible environment if we are trying to reduce infectious disease,” Zinzi Bailey told SciFri earlier this week on the phone. She is a social epidemiologist at the University of Miami and a principal investigator of the COVID Prison Project, which tracks and analyzes coronavirus data in U.S. correctional facilities. “A lot of people would argue that the conditions are inhumane.” Disease outbreaks have swept through prisons in the past, often due to poor living conditions and limited access to proper health care, Bailey explains. Hepatitis, tuberculosis, and HIV are just a few of the diseases that have historically hit inmates hard. Now, the incarcerated, correctional officers, and staff members are battling COVID-19. Detention centers are notoriously overcrowded, making it easy for the virus to spread. The cramped, dormitory-style living conditions, shared spaces, and infrequent sanitation can contribute to increased risk of exposure and infection. In Ohio, for example, the prison system is at 130% capacity, making it “basically impossible” to socially distance inmates, Paige Pfleger, health reporter at WOSU in Columbus, Ohio, told SciFri on the phone last week.  Yet incarcerated people living in these conditions have little to no access to protection. Some have resorted to making face coverings out of shirts and boxer shorts. At the beginning of the pandemic, some correctional officers in Arizona prisons were not allowed to wear masks.  “Correctional officers were originally told that if they did wear masks, it would scare inmates—that they’re going to think, ‘Oh my gosh, this is a really serious virus,’” says Jimmy Jenkins, senior field correspondent and criminal justice reporter at KJZZ in Phoenix, Arizona. “I got letters from all these inmates saying they were scared of dying.” Access to testing among the incarcerated population has also varied state to state. Ohio conducted mass tests in some of the facilities in April, but have been unable to retest in order to track community spread, says Pfleger. In Arizona, inmates are reporting that “only the sickest of the sick are actually getting tested,” says Jenkins. Coronavirus outbreaks in prisons often spill over into the rest of the community. Contract workers and correctional officers coming in and out of detention facilities can cause further spread of the virus. This is concerning, particularly in Black, Latino, and Native American communities with an already increased risk of contracting the disease. “We believe that there’s going to be a connection between the communities of color that are around prisons, and the prisons themselves,” says John Eason, an assistant professor of sociology at the University of Wisconsin-Madison, who spoke to Science Friday over the phone earlier in the week. In an ongoing study with the Dane County Criminal Justice Council, “we’re going to be able to parse that out to see the role of corrections officers.” He suspects they may find officers are “basically incubators—or vectors between communities and the prisons that they work in.” The inmates are like “guinea pigs,” says Zinzi Bailey. “It’s like an experiment, and we are letting it run its course in these prisons,” she says—but one without an ethical review. “What is being made clear through this pandemic is the United States’ reliance on incarceration makes us more vulnerable to pandemics like this.” Paige Pfleger and Jimmy Jenkins tell us more about how their states are responding to coronavirus outbreaks in prisons. Then, social epidemiologist Zinzi Bailey provides a closer look at the trends in American prisons—and what COVID-19 is revealing about public health in these systems.  We didn’t always understand the basic science of where babies come from. Theories abounded, but until the 19th century, there was little understanding of how exactly pregnancy occurred, or even how much each parent actually contributed to the reproductive process.  In 1677, a Dutch scientist named Antonie van Leeuwenhoek peered into a microscope and observed, for the first time in recorded history, the side-to-side swimming of tiny sperm cells. He wrote they looked like “an eel swimming in water.” At the time, van Leeuwenhoek thought those cells were tiny worms—maybe even parasites. It took several hundred more years before scientists understood even the crude theory of reproduction as most of us are taught: That a sperm and an egg cell combine inside the fallopian tubes. But, as it turns out, even the movement of sperm first described by van Leeuwenhoek—and corroborated ever since in two-dimensional, overhead microscope views—might be wrong. A team of scientists writing in the journal Science Advances this week report finally viewing sperm movement in three dimensions. With the help of 3D microscopy and high-speed photography, they describe a “wonky,” lopsided swimming motion that would keep sperm swimming in circles—if they didn’t also have a corkscrew-like spin that let them move forward “like playful otters.” Hermes Gadelha, a senior lecturer in mathematical and data modeling at the University of Bristol in the United Kingdom, talks to John Dankosky about the complexity and beauty of these swimming cells, and why understanding their movement better could lead to breakthroughs in infertility treatment—or even other kinds of medicine. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Astronauts have conducted all sorts of experiments in the International Space Station—from observations of microgravity on the human to body to growing space lettuce. But recently, cosmonauts bioengineered human cartilage cells into 3D structures aboard the station, using a device that utilizes magnetic levitation.  The results were recently published in the journal Science Advances. Electrical engineer Utkan Demirci and stem cell biologist Alysson Muotri what removing gravity can reveal about basic biological questions, and how you design experiments to run in space.  Major League Baseball’s season opened to great fanfare last week, amid the pandemic. But 18 players and staff of the Miami Marlins have already tested positive for COVID-19—forcing the team to pause their season until at least next week. Meanwhile, the NBA has quarantined their entire roster in a bubble in the Magic Kingdom in Florida.  Sports reporter Ben Cohen and epidemiologist Zachary Binney talk about the strategies and effectiveness of different leagues as competitive sports attempt to make a COVID-19 comeback.  Ketchup has long been central to American culture. We use it in hot dogs, burgers, fries—and the list goes on. But have you ever wondered why we even call it ‘ketchup,’ or where the condiment came from?   It turns out there are many words related to food—like restaurant, umami, and “rocky road”—that have an interesting science backstory. To trace the origins of these words, Science Friday’s word nerd Johanna Mayer joins John Dankosky to talk about the origins of the word ketchup, and the new season of her podcast ‘Science Diction.’ As American pharmaceutical company Moderna’s COVID-19 vaccine candidate entered Phase 3 of human clinical trials this week—an important step in what is still an early phase of its development—Russia claims a vaccine of its own will be approved for use as soon as mid-August, prompting safety concerns. But questions about vaccines extend far beyond who is first. What happens next for the people around the world waiting for protection from the pandemic? As Science Magazine reports, rich nations have placed hundreds of millions of advance orders for successful vaccines, while poorer countries worry that there will be little left for everyone else. Maggie Koerth, senior science reporter for FiveThirtyEight, discusses this story and more news from the week, including the discovery of 100-million-year-old microbes living beneath the ocean floor.   Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.