Memory And The Dreaming Mind
If you’ve ever stayed up too late studying for a test, you know that sleep impacts memory—you need that precious shut-eye in order to encode and recall all that information. But what is it about sleep that aids memory?
Researchers have pinpointed a specific stage of sleep, REM sleep, as an area of interest for studying memory consolidation. REM, or rapid eye movement sleep, is the same stage in which dreams occur. So researchers at Northwestern University devised a way to communicate with lucid dreamers—people who are aware of their dreams and can control what they do in them—as a way to study how memories get made.
Science Friday producer Katie Feather talks with Ken Paller, professor of psychology at Northwestern University to discuss what lucid dream research has taught us about memory.
Progress In Considering Sex As A Biological Variable
Back in 2013, Charles Hoeffer from the University of Colorado Boulder was studying memory and learning in mice. He was looking at a specific protein in the brain called AKT1, which helps mice forget an old task and learn a new one. In humans, a mutation in that protein has been linked to disorders like schizophrenia, Alzheimer’s and depression.
But in a follow-up study, Hoeffer did something different. He included both male mice and female mice, and then tested them separately. As expected, he discovered that male mice had a much tougher time learning the task when AKT1 wasn’t working. But in female mice, he found the unexpected: It didn’t make any difference whether the protein was removed or not. In other words, the sex of the mouse became an important variable that affected the outcome of the research.
Hoeffer’s study is one example of considering sex as a biological variable (SABV) in pre-clinical research. And in 2016, the National Institutes of Health’s Office of Research on Women’s Health made it an official policy for researchers applying for funding.
But that didn’t change things overnight. Five years later, the approach is still catching on in many areas of research. Chyren Hunter, from the Office of Research on Women’s Health, joins Ira to discuss the progress that’s been made, and what lies ahead for the effort to make pre-clinical research more inclusive.
Further information on the NIH’s policy on sex as a biological variable is on its website.
The Problem With ‘Parachute Science’
“Parachute science” is a term describing how researchers sometimes drop down from an ivory tower in the wealthy Western world into a foreign community for field work. They gather their data, and then zip off home without engaging with or acknowledging the contributions of the local researchers in that community. This week in the journal Current Biology, researchers tried to quantify just how widespread that tendency is in one area of study—coral reefs.Searching through fifty years of publications published on the topic of warm water coral reef biodiversity research, they found that in 22% of the studies on coral reef ecosystems in Australia, there were no Australian researchers included as authors on the publication. The effect was even more noticeable in lower-income countries, such as Indonesia and the Philippines—where 40% of the published studies on coral reefs included no local scientists.
Ira talks with two of the study’s authors, Paris Stefanoudis and Sheena Talma, about what they found, and how researchers can work to make science more inclusive.
The Global COVID-19 Supply Problem
Of the more than 200 million COVID-19 vaccines that have made it to patients’ arms this winter, more than a quarter have gone to people in the United States—a country with 4 percent of the total world population. Just last week, UN Secretary-General Antonio Guterres said that 75% of the world’s vaccinations so far had been in just 10 countries—while 130 countries had not received a single dose.
Meanwhile, on Wednesday, the nation of Ghana was the first to receive vaccines—600,000 doses—shipped as part of COVAX, a multi-national program which aims to provide as many as two billion free vaccines to poor and middle-income countries by the end of the year.
Ira talks to Yale global health expert Saad Omer about the international effort to move vaccines equitably around the world, and the remaining hurdles for poorer countries.
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Covering the outer reaches of space to the tiniest microbes in our bodies, Science Friday is the source for entertaining and educational stories about science, technology, and other cool stuff.
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Folge vom 26.02.2021Lucid Dreaming, Sex As A Biological Variable, Parachute Science, Global Vaccine Access. Feb 26, 2021, Part 2
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Folge vom 19.02.2021Tech Unions, Color Perception, Fish Vs Birds. Feb 19, 2021, Part 2Reprogramming Labor In Tech More than 6,000 warehouse workers in Bessemer, Alabama are midway through voting on whether they should unionize. If the ‘yes’ votes win, it would be unprecedented for the company: The last time a unionization vote was held by Amazon’s United States employees, back in 2014, a group of 30 technicians ultimately voted not to join the International Association of Machinists and Aerospace workers. Meanwhile, at Google, a group of more than 800 have recently joined the Alphabet Workers Union, which was formed in early January. The AWU is a minority union, a kind of union that cannot negotiate contracts. But, the union has said, they will still be able to advocate for workers who would be excluded from a traditional union, like the temporary workers, contractors, and vendors who make up more than half of Google’s global workforce. And in the world of app-based gig workers, a debate has been raging for years about whether Uber and Instacart workers are full employees with rights to overtime and collective bargaining—or contractors, which have neither. In California, state law has changed twice in the last year to try to answer this question. SciFri producer Christie Taylor talks to legal scholar Veena Dubal, and historian Margaret O’Mara, about this rise in union activity, and the way tech companies have impacted our lives—not just for their customers, but also for their workers. Fish Versus Feather: Georgia’s Salt Marsh Smackdown At Science Friday, we love a smackdown, whether it’s a debate over which mammal has better sonar—dolphins versus bats—or which planet is the best to host signs of life—Mars or Venus? But when it comes to fish versus birds, we don’t need to manufacture drama. Nature gave us its own. Corina Newsome, a graduate student at Georgia Southern University, was studying how seaside sparrows adapt to nest flooding, an environment where the most likely predators are animals like minks and raccoons. That’s when she caught on film a very unusual interaction: A fish entered a sparrow’s nest, and killed one of the new hatchlings. Newsome joins Ira to explain what she saw, and how climate change is helping to turn the tables on this predator-prey relationship. The Neuroscience Behind Seeing Color The basic mechanics of how we see color sounds simple enough—light hits an object and bounces into our eye. Then, our brain processes that information. But how we perceive color is much more complicated. Neuroscientist and artist Bevil Conway is mapping out how the neurons in our brain respond to color to make a neurological color model. He explains how color might encode meaning, and the plasticity of our visual system. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Folge vom 19.02.2021Fauci On Vaccines and Variants, Mummy Mystery, Texas Power Grid Failure. Feb 19, 2021, Part 1Fauci Says Majority Of U.S. Adults Likely To Be Vaccinated By Late Summer We’re about a month shy of a big anniversary: one year since the World Health Organization officially labeled COVID-19 a pandemic. Since then, a lot has changed—and a lot has not. We have more information than ever about COVID-19, but there are still a lot of unknowns about the illness. While about 40 million people in the U.S. have received at least one dose of a vaccine, it’s unclear when we can expect to return to a sense of normalcy. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, joins Ira to shed some light on the latest news about variants and vaccines—and the light at the end of the COVID-19 tunnel. He predicts vaccines are likely to be open to all adults starting in May or June. “By the time you get everyone vaccinated who could be vaccinated, that’s going to take several months,” Fauci says. “So it won’t be until the end of the summer.” Fauci and Ira also discuss when it’s ok for families to get together without a laundry list of precautions, as well as his legacy from decades at the NIH. Uncovering An Ancient Mummy Mystery Ever since the discovery of King Seqenenre-Taa-II’s mummy in Egypt in the mid-1800s, it was clear that the king had met an untimely demise. His hands were clenched in a claw-like gesture, and the pharaoh’s head bore several fatal wounds. But the exact nature of his death was lost to time: Had he died in some sort of palace intrigue? Or was he executed? Writing in the journal Frontiers in Medicine, radiologist Sahar Saleem and her collaborators argue that a CT scan of the mummy supports the theory that the king died during conflict with the Hyksos, an Asian group that invaded and controlled northern Egypt. The researchers say that the wounds and other signs on the body suggest the king was captured, bound, and executed by multiple assailants. SciFri’s Charles Bergquist spoke with Saleem about her research, and how it fills in clues about the ancient mystery. Why Did The Texas Power Grid Fail? More than 500,000 Texans were still without power Thursday as another round of snow and ice moved through the state, three days after a historic wave of cold and snow that prompted the state power regulator to initiate rolling blackouts in an effort to prevent a larger, months-long outage. But as Texans remain without power in freezing temperatures, the side-effects of infrastructure failure are their own disaster: people freezing in their homes, risking carbon monoxide poisoning, or struggling to get food and water. Why was the electric grid so damaged by winter weather? The MIT Technology Review’s Amy Nordrum explains the fragility of Texas’ power grid, and how a lack of winterized infrastructure has ripple effects for the whole state. Plus, she talks about the successful landing of NASA’s Perseverance rover on Mars, new smells in the toolbox against invasive bark beetles, and more recent science stories. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Folge vom 12.02.2021Fish Eye Secrets, Human Genome Project, Science Diction 'Mesmerize.' Feb 12, 2021, Part 2Seeing The World Through Salmon Eyes The saying goes, “The eyes are the window to the soul.” But for fish, the eyes are the window to the stomach. As one California biologist recently learned, the eyes of Chinook salmon are like a tiny diet journal of everything it ate. But to read that journal, you have to peel back the layers of the eye, like it’s the world’s tiniest onion. Miranda Tilcock, assistant research specialist at the Center for Watershed Science at the University of California, Davis talks to Ira about why she goes to such gooey lengths to understand what these salmon eat. Two Decades Beyond The First Full Map Of Human DNA In February 2001, the international group of scientists striving to sequence the human genome in its entirety hit a milestone: a draft of the complete sequence was published in the journals Nature and Science. The project took 13 years to complete: In that time, genome sequencing became faster and cheaper, and computational biology ascended as a discipline. It laid the groundwork for the greater cooperation and open data practices that have made rapid vaccine development possible during the pandemic. In the decades since, researchers have been trying to better understand how genetics impact health. We’re still working toward the dream of personalized treatments based on a person’s specific genetic risks. Ira looks back at the successes and challenges of the Human Genome Project with Shirley Tilghman, a molecular biologist who helped plan the project, and served on its advisory committee. Then, with bioinformatician Dana Zielinski and Indigenous geneticist-bioethicist Krystal Tsosie, he looks to the contemporary hurdles for genetic research, including privacy, commercialization, and the sovereignty of Indigenous peoples over their own genetic data. Meet The Man Behind The Word ‘Mesmerize’ In the 18th century, a man named Franz Anton Mesmer came to Paris with a plan: to practice a controversial form of medicine involving magnets and gravity. Mesmer claimed his treatments cured everything from toothaches to deafness. His critics, however, weren’t so sure about that. Mesmer made enemies in high places, labeling him a con, and calling his type of practice “mesmerism.” The story behind the word “mesmerize,” and other words about mind control are the focus of season three of Science Diction, a podcast about words and the science behind them from Science Friday. Joining Ira to talk about the story behind “mesmerize,” and what else is coming this season is Science Diction host, Johanna Mayer. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.