Before any new drug comes to market, it goes through a time-consuming process. Researchers have to recruit human subjects for a clinical trial, collect all the data, and analyze the results. All of that can take years to complete, but the end result could be worth it: a drug that treats a rare disease or improves patients lives with fewer side effects.
Or the opposite could happen: The drug doesn’t have any effect or makes patients worse. So the question is, how is the public informed of the outcome?
One answer is ClinicalTrials.gov, a public-facing website where researchers are required by law to register all currently ongoing clinical trials and report their results. That way, the public is kept informed.
However, two recent investigations of ClinicalTrials.gov reporting practices show that many researchers aren’t posting their results online. In fact, up to 25% of studies never seem to have their results reported anywhere. And government agencies aren’t enforcing the rule in ways they’ve promised—with heavy fines and threats to withhold funding from institutions that don’t comply.
In a delicate piece of shale from coastal China, paleontologists have identified a new species of feathered dinosaur: Wulong bohaiensis, Chinese for “Dancing Dragon.” The house cat-sized dino has fierce talons, feathered wings, and a long, whip-like tail with feathered plumes at the end.
Ashley Poust, who published a description of the dinosaur in The Anatomical Record, says it’s “hard to imagine” the wings being used for flying. But he says the wings could have been used to arrest leaps or falls, or to hold down prey while killing it, as modern-day birds sometimes do.
In this conversation with Ira, Poust talks more about the dino’s possible lifestyle, and how it fits in with other feathered reptiles.
A cup of coffee first thing in the morning is a ritual—from grinding the beans to boiling the water and brewing your cup. But following those steps won’t always get you a consistent pour. Researchers developed a mathematical model to determine how the size of grind affects water flow and the amount of coffee that gets into the final liquid. Their results were published in the journal Matter.
Computational chemist Christopher Hendon, who was an author on that study, talks about how understanding atomic vibration, particle size distribution, and water chemistry can help you brew the perfect cup of coffee.
Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
Talk
Science Friday Folgen
Covering the outer reaches of space to the tiniest microbes in our bodies, Science Friday is the source for entertaining and educational stories about science, technology, and other cool stuff.
Folgen von Science Friday
1192 Folgen
-
Folge vom 24.01.2020Feathered Dino, Clinical Trials, Coffee Extraction. Jan 24, 2020, Part 2
-
Folge vom 17.01.2020Polling Science, Gar-eat Lakes. Jan 17, 2020, Part 1The Science Of Polling In 2020 And Beyond In today’s fast-paced digital culture, it is more difficult than ever to follow and trust political polls. Campaigns, pollsters, and media outlets each say that their numbers are right, but can report different results. Plus, the 2016 election is still fresh in the public’s mind, when the major story was how political polling got it wrong. But despite how people may feel about the practice, the numbers suggest that polls are still working. Even as telephone survey response rates have fallen to around 5%, polling accuracy has stayed consistent, according to a new report published by the Pew Research Center. But things get even trickier when talking about online polls. So how can polling adapt to the way people live now, with texting, social media, and connecting online? And will the public continue to trust the numbers? Ira talks with Courtney Kennedy, director of survey research at the Pew Research Center about the science of polling in 2020 and beyond. Kennedy also told SciFri three questions you should ask when you’re evaluating a poll. Find out more. Why Native Fish Matter The fish populations of the Great Lakes have changed dramatically in the years since invasive species first arrived. Bloodsucking sea lampreys have decimated native lake trout, and tiny alewives have feasted on the eggs and young of trout and other native species. But there’s good news too, as researchers roll out solutions to help manage invasive fish populations and maintain the diversity of species. In this next installment of the SciFri Book Club, Fish ecologist Solomon David explains why the biodiversity of the Great Lakes matters more than ever, and how to appreciate these hard-to-see freshwater fish. Planning For Spring Waters Along The Missouri In Missouri, people are looking towards repaired levees in the hopes of reducing future flood damage. Our Bodies Are Cooling Down 98.6 F is no longer the average healthy body temperature. Is improving health the culprit? Science journalist Eleanor Cummins reports the latest in science news. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
-
Folge vom 17.01.2020Biorobots, The Math Of Life, Science Comics. Jan 17, 2020, Part 2Living Robots, Designed By Computer Researchers have used artificial intelligence methods to design ‘living robots,’ made from two types of frog cells. The ‘xenobots,’ named for the Xenopus genus of frogs, can move, push objects, and potentially carry materials from one place to another—though the researchers acknowledge that much additional work would need to be done to make the xenobots into a practical tool. The research was published in the Proceedings of the National Academy of Sciences. Josh Bongard, a professor of computer science at the University of Vermont and co-author of the report, joins Ira to talk about designing cell-based structures and next steps for the technology. The Math Behind Big Decision Making What does it mean for your health if a cancer screening is 90% accurate? Or when a lawyer says there’s a 99% chance a defendant is guilty? We encounter numbers in our everyday lives that can influence how we make big decisions, but what do these numbers really tell us? Mathematical biologist explores these concepts and patterns in his book The Math of Life and Death: 7 Mathematical Principles That Shape Our Lives. He joins Ira to talk about the hidden math principles that are used in medicine, law, and in the media and how the numbers can be misused and correctly interpreted. The Science Comics Of Rosemary Mosco Have you ever wondered what a Great Blue Heron would write in a love letter to a potential mate? Or what the moons of Mars think of themselves? These are the scenes that nature cartoonist Rosemary Mosco dreams up in her comic Bird and Moon. “Nature is really funny. It’s never not funny,” Mosco says in SciFri’s latest SciArts video. “You can go into the woods and find 20 or 30 hilarious potential comic prompts anywhere you go.” Viewers may come for the laughs, but they will end up learning facts, she explains. Mosco talks about her inspiration for finding the funny side of snakes, planets, and nature, and how she uses humor to communicate science. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
-
Folge vom 10.01.2020Migraines, Galaxy Formation. Jan 10, 2020, Part 2The Mysteries Of Migraines What do sensitivity to light, a craving for sweets and excessive yawning have in common? They’re all things that may let you know you’re about to have a migraine. Of course each person’s experience of this disease—which impacts an estimated 38 million people in the U.S.—can be very different. One person may be sensitive to light while another is sensitive to sound. Your pain may be sharp like a knife while your friend’s may be dull and pulsating. Or perhaps you don’t have any pain at all, but your vision gets temporarily hazy or wiggly. This week Ira is joined by two migraine experts, Elizabeth Loder, of Brigham and Women’s Hospital and Harvard Medical School, and Peter Goadsby, professor of neurology at the University of California San Francisco, who explain what’s going on in the brain of a migraineur to cause such disparate symptoms. Plus, why some treatments work for some and not others, from acupuncture and magnesium supplements, to a new FDA approved medication that goes straight to the source. How Do Galaxies Get Into Formation? The Milky Way and distant galaxies are a mix of gas, dust, and stars. And while all of this is swirling in space, there is a structure to a galaxy that holds all of this cosmic dust in order. A group of researchers discovered a nearly 9,000 light year-long wave of “stellar nurseries”—star forming regions filled with gas and dust—running through the Milky Way, and could form part of the galaxy’s arm. The study was published in the journal Nature. Astronomers Alyssa Goodman and Catherine Zucker, who are authors on that study, tell us what this star structure can tell us about the formation of our galaxy. Plus, astrophysicist Sangeeta Malhotra talks about one of the oldest galaxies formed 680 million years after the big bang, and the difference between these ancient galaxies and our own. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.