Cancer, at its core, is a genetic disease: the result of DNA mutations that cause cells to grow out of control and develop tumors. And over the years, scientists have identified certain chemicals, called carcinogens, that are directly linked to those cancer-causing mutations, like those found in cigarettes.But the rates of some cancers, like colorectal and lung, are rising dramatically in certain populations, leaving scientists to wonder what carcinogens they might be missing, and how traditional models of detecting them are falling short.Last year, a landmark study published in the journal Nature confirmed a theory that toxicologists and cancer researchers had long suspected: that certain chemicals, like those found in air pollution, may not directly lead to cancerous mutations, but instead prime already vulnerable mutated cells to become cancerous. Some scientists have dubbed these chemicals “dark matter” carcinogens; they know they’re out there, exerting some kind of effect on increasing cancer rates, but they don’t fully understand what these chemicals are.Dr. Siddhartha Mukherjee, Pulitzer Prize-winning author and assistant professor of medicine at Columbia University, wrote about this scientific detective mystery in The New Yorker. This week, he joins Ira to talk about how scientists are rethinking their approach to identifying carcinogens, and why he’s hopeful for the future of cancer research in light of this new paradigm.Transcripts for this segment will be available the week after the show airs on sciencefriday.com.
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Covering the outer reaches of space to the tiniest microbes in our bodies, Science Friday is the source for entertaining and educational stories about science, technology, and other cool stuff.
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Folge vom 05.02.2024Scientists Are Uncovering A World Of ‘Dark Matter’ Carcinogens
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Folge vom 02.02.2024Syphilis Cases Up 80% Since 2018 | The Largest Deep-Sea Coral Reef In The WorldThere has been a boom of syphilis cases, including a 180% increase in congenital syphilis cases, despite other STI levels staying stable. Also, the world's largest deep-sea reef stretches for hundreds of miles in near-freezing waters and total darkness, but it’s bustling with life.Syphilis Cases Are Up 80% Since 2018Syphilis is rearing its ugly head again in the United States. A new report on sexually transmitted infections (STIs) from the Centers for Disease Control and Prevention shows a shocking statistic: Cases of syphilis are up by nearly 80% among adults since 2018. Congenital syphilis cases, which occur when an infection is passed from parent to child during pregnancy, are up by more than 180%.Strangely, cases of other STIs have stayed about the same or decreased in the same timeframe. Rachel Feltman, host of “The Weirdest Thing I Learned This Week,” joins Ira to talk about this and other science stories from the week, including the first cases of transmitted Alzheimer’s disease, and why closing the toilet seat doesn’t keep aerosolized viruses from contaminating other bathroom surfaces.Revealing The Largest Deep-Sea Coral Reef In The WorldScientists recently discovered the largest known deep-sea coral reef in the world. It’s called Million Mounds, and it stretches from Miami, Florida, to Charleston, South Carolina, covering around 6.4 million acres of the seafloor.Unlike the colorful reefs found in sunlit tropical waters, this one is mostly made up of a stony coral that’s usually found from about 650 to 3,300 feet underwater—depths where it’s very cold and pitch black.Ira Flatow talks with Dr. Erik Cordes, marine biologist and professor at Temple University in Philadelphia, Pennsylvania, who collaborated on the study. They discuss what makes deep-sea corals different from those found in shallower waters, why it’s important to map them, and what it’s like to visit one in a submarine.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Folge vom 01.02.2024Expanding Our Umwelt: Understanding Animal ExperiencesTake a quick moment to think about your surroundings. Tune into your senses, and contemplate what’s happening around you. What do you see, hear, and smell? Now take a moment to imagine: What if you were a bat? How would you experience your environment differently? Maybe you could sense a nearby spider through echolocation, or feel minute changes in air pressure and temperature to know where to fly next. This world of perception is unique to each organism. It’s what scientists call umwelt, from the German word meaning “environment” or “surroundings,” and it is the subject of this month’s SciFri Book Club pick.Science writer, author, and birder Ed Yong returns to talk about how senses both familiar and foreign to us help animals experience their environment, and to tell us what he’s learned in the past year since his book, An Immense World: How Animal Senses Reveal The Hidden Realms Around Us (now available in paperback), was published.The SciFri Book Club read An Immense World together this January, and readers joined Yong and guest host Arielle Duhaime-Ross via a live Zoom Call-in for a conversation on how writing about animals changed his experience in nature, how educators can help students become better connected to the Earth, and how readers are still connecting with his work on the umwelten of the animal kingdom.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Folge vom 31.01.2024How Signing Characters Help Deaf Children Learn LanguageThis radio interview is an abbreviated version of the full video interview, available with ASL interpretation on Youtube.Think back to your favorite childhood TV show—was it “Blue’s Clues”? “Little Bear”? “Winnie the Pooh”? Animated TV shows are important for kids because they can teach them to read, draw, spell, and talk. Plus, the ways these shows tell stories and create colorful, fictitious worlds can broaden children’s knowledge and capacity to imagine.But children’s shows aren’t accessible to all deaf children, which means they could miss out on a common learning experience. Among other things, that can set kids back in learning both American Sign Language (ASL) and English language skills during their formative early childhood years.Melissa Malzkuhn is third-generation Deaf and the founder and director of the Motion Light Lab at Gallaudet University in Washington, D.C. Her lab is creating ASL-focused children’s media that is made by and for the Deaf community, using motion capture technology, avatars, animation, and signing storytellers. She talks with guest host Arielle Duhaime-Ross about ASL access in childhood, the science of learning, and how she’s creating “Here Comes Mavo!”—the first animated TV series with signing characters.Transcripts for this segment will be available the week after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.